Abstract: The technique of stabilizing piles with pre-stressed anchored cables is an effective measure in landslide remediation works, which nowadays has a wide application in many fields. However, the design and calculating methods of this technique need more attention and urgent research work. Stabilizing piles with pre-stressed anchored cables are a development of the technique of using stabilizing piles. Compared to the use of stabilizing piles alone, anchored cables make the state of the forces on piles more reasonable. A mechanical and mathematical model of piles with pre-stressed anchored cables has been set up, based on a geological and physical model of this landslide stabilizing system. This model establishes the foundation of the calculations for the structural design of the system. The analytical and numerical solutions of the established mathematical model have been achieved. The "two-parameter method" is employed to calculate the coefficient of subgrade reactions or subgrade modulus. The two models, of rigid and elastic piles respectively, are discussed, in which the anchored cable is regarded as an elastic hinge. Under the consideration of deformation harmony between anchored cables and the pile body, the tensile force of anchored cables has been obtained, as well as a solution for internal force distribution along the pile body. A case study in the reservoir areas of the Three Gorges Project is presented in the last part of the paper, in which the application of this technique in landslide remediation works is analyzed and discussed in detail.