Abstract: Taking a landslide area in Guangdong Province as the research object, Visual MODFLOW is used to process the elevation data of landslide area and establish an accurate 3D model combined with the geological exploration report of landslide area. After the three-dimensional landslide model is established, the corresponding model parameters are calculated and input through the field hydrogeological test data. Then, the numerical inversion method is used to simulate the hydrogeological test process. By inversion of hydrogeological parameters, the numerical simulation results of observed well water level at different positions are consistent with the actual measurement results. Thus, the hydrogeological parameters closest to the actual site are determined. In this paper, the hydrogeological parameters of the landslide area are obtained from both numerical simulation and theoretical calculation, and the results obtained by the two methods are not very different. Therefore, the numerical simulation method adopted in this paper can more conveniently obtain the hydrogeological parameters of the landslide area. The obtained data can be used to accurately evaluate the influence of groundwater on landslide, and provide scientific basis for landslide prevention and control and improvement of regional hydrogeological conditions.