Since the 90s, 20th century, the construction of big traffic bridges across middle-lower reaches of the Changjiang River has stepped into fast development. So far, bridges in Huangshi, Tongling, Jiangyin, Wuhan, and Nanjing have been in transport service. Still, some bridges are under construction and design. Various engineering geological problems have occurred, such as fault, soft interlayers, extreme softrocks, karst caves, and so on. In addition to common methods of investigation and mechanical test, the rheology test of softrocks, color video recordings, the field bearing test, and the pier analogue simulating have been taken to deal with the problems. The practice has provided dependable data for bridge design, which has been proved successful in the construction of bridges, and will be of treasury experience for the future bridge construction in middle-lower reaches of the Changjiang River.