Abstract: The separate and static management status of geology information hasn't been able to meet the market economy's development and variety, scientificity and imminence of widely social demands, also extremely restrict the total exertion of social economy benefits of geology information. According to the achieved results of regional multi-source geology spatial information integration projects, based on GIS theory and technique and the characteristics of multi-source geological information spatial data application, the discussion of technical methods about regional multi-source geology spatial information integration is given, and also narrates in details the programming and design of multi-source geological geographical information system, the capturing techniques of data, metadata, the projection, reference frame, the physical design and stipulation as well as the features of the quality of integration data.